Medications

Here is a list of all medications known to AneIV.
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Opioids

Opioids often used in anesthesia.

Alfentanil 0.5 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Dose depending on duration of surgery.

Alfentanil 0.5 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  NA

Fentanyl 50 mcg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  NA

Morphine 1 mg / ml (Bolus)

• Reference(s): No reference
• Comment:
  NA

Remifentanil 50 mcg / ml (Infusion)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Be aware of bradycardia.

Sufentanil Citrate 50 mcg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  As analgetic adjunct to induction.

  Maintenance 10-50 mcg

Sufentanil Citrate 50 mcg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Maintenance dose if sign of light anesthesia

Hypnotics

Hypnotics often used in anesthesia.

Dexmedetomidine 4 mcg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Loadingdose if patient does not have any other sedative.

Dexmedetomidine 4 mcg / ml (Infusion)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Maintenance dose expressed as mcg/kg/hour

  Limited data regarding children See references

  Remember loadingdose if not already sedated

Etomidate 2 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Maintenance of anesthesia.

  Children above 10 years of age, refer to adult dosing.

Etomidate 2 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Induction of anesthesia.

  Children above 10 years of age, refer to adult dosing.

Ketamine 10 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  NA

Ketamine 10 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Alternative to continouse infusion is to administer supplemental doses of one-half to the full induction dose every 10-15 minutes or a continuous infusion of 0.1 to 0.5 mg/minute.

Ketamine 50 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  NA

Ketamine 50 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Alternative to continouse infusion is to administer supplemental doses of one-half to the full induction dose every 10-15 minutes or a continuous infusion of 0.1 to 0.5 mg/minute.

Ketamine 50 mg / ml (IM)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Consider administering atropine, glycopyrronium, scopolamine or another drying agent prior to induction and at appropriate intervals to decrease hypersalivation,

  Pediatrics
  3 to 7 mg/Kg IM

  Adults Induction

  Manufacturers labeling IM is 6.5-13 mg/Kg
  Others suggest 4-10 mg/Kg
  Lower doses can bu used if adjuvant drugs such as midazolam, are administered.

Lorazepam 2 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Pediatrics
  Status epilepticus : 0.05-0.1 mg/Kg maximum 4 mg per dose over 2-5 minutes repeated if necessary every 5-15 minutes. Normal total dose 8 mg.
  Acute anxiety :
  Children younger than 12 years : IV 0.05 mg/Kg per dose. Maximum 2mg / dose

  Adults
  Premedication anesthesia : IV 0.044 mg/Kg. Normally 2 mg, not more than 4 mg. If patient is older than 50 years, give 2 mg.
  Status epilepticus : 0.1 mg/Kg, maximum 4 mg at maximum 2 mg/minute.

Midazolam 1 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Sedation in mechanically ventilated patients, initial dose

Midazolam 1 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Sedation in mechanically-ventilated patients, maintenace.

Propofol 10 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  General anesthesia.

Propofol 10 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  General anesthesia.

  Small doses for eldery and debilitated patients in all ages.

Propofol 10 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Sedation in mechanically ventilated patients.

Thiopental 25 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  General Anesthesia.

Pressors

Drugs often used to increase bloodpressure.

Dobutamine 500 mcg / ml (Infusion)

• Reference(s): [ 1 ] [ 2 ] [ 3 ] [ 4 ]
• Comment:
  In patients with heart failure, lower maintenance doses are preferred to minimize adverse effects.

  A maximum dose of 20 mcg/kg/minute is recommnede by The ACCF/AHA 2013 heart failure guidelines and the Surviving Sepsis Campaign.

Dobutamine 1000 mcg / ml (Infusion)

• Reference(s): [ 1 ] [ 2 ] [ 3 ] [ 4 ]
• Comment:
  In patients with heart failure, lower maintenance doses are preferred to minimize adverse effects.

  A maximum dose of 20 mcg/kg/minute is recommnede by The ACCF/AHA 2013 heart failure guidelines and the Surviving Sepsis Campaign.

Dobutmaine 2000 mcg / ml (Infusion)

• Reference(s): [ 1 ] [ 2 ] [ 3 ] [ 4 ]
• Comment:
  In patients with heart failure, lower maintenance doses are preferred to minimize adverse effects.

  A maximum dose of 20 mcg/kg/minute is recommnede by The ACCF/AHA 2013 heart failure guidelines and the Surviving Sepsis Campaign.

Dopamine 1 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  < 5 mcg/kg/minute increased renal blood flow and urine output. 5-15 mcg/kg/minute increased renal blood flow, heart rate, cardiac contractility and cardiac output. > 15 mcg/kg/minute alphaadrenergic effects begin to predominate vasoconstriction increased blood pressure.

Epinephrine 10 mcg / ml (Infusion)

• Reference(s): No reference
• Comment:
  Hypotension or shock.

Milrinone 200 mcg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Administered over 10 minutes followed by a maintenance infusion.

Milrinone 200 mcg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Maintenanceinfusion.

Norepinephrine 10 mcg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Hypotension or shock. Shows ncg and not mcg as used in reference.

Norepinephrine 20 mcg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Hypotension or shock. Shows ncg and not mcg as used in reference.

Norepinephrine 40 mcg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Hypotension or shock. Shows ncg and not mcg as used in reference.

Norepinephrine 50 mcg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Hypotension or shock. Shows ncg and not mcg as used in reference.

Norepinephrine 80 mcg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Hypotension or shock. Shows ncg and not mcg as used in reference.

Norepinephrine 100 mcg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Hypotension or shock. Shows ncg and not mcg as reference.

Phenylephrine 0.1 mg / ml (Infusion)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Hypotension or shock.

  Children : see references.

  Adults : First reference says 0.5 mcg / kg / minute up to 9 mcg / kg / minute.
  Adjusted minimumdose to fit second reference.

  Hypotention during anesthesia initial dose is 10 – 35 mcg / minute not to exceed 200 mcg / minute.

  Or keep below these doses : 10 to 35 mcg/minute adjusted according to blood pressure goal, not to exceed 200 mcg/minute.

Phenylephrine 0.1 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Hypotensjon or shock.

  Children : See references

  Adults :

  During anesthesia, bolusdoses of 40 – 100 mcg might be sufficient.

  Adultdoses related to shock is max 500 mcg.

Muscle Relaxants

Neuromuscular blockers.

Atracurium 10 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Initial dose.

  Infants and children between 1 month and 2 years : 0.3 to 0.4 mg/kg. Else same dose as adults. With adults, calculate dose based on ideal body weight.

  Maintenance bolus dose 0.08-0.1 mg / kg as needed.

  Concider reducing initial dose to 0.3 to 0.4 mg/kg if patients has significant cardiovascular disease or a known history of elevated risk of histamine release.

  First dose after succinylcholine for intubation is 0.3 to 0.4 mg/kg.

Atracurium 10 mg / ml (Infusion)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  As neeed to maintain neuromuscular block.

  Infants and children below the age of 2 years:
  normally between 6 to 14 mcg/kg/minute

Cisatracurium 2 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Intubatingdoses.

  If patient is intubated using succinylcholine, initial dose Cisatracurium is 0.1 mg/kg.

  Maintenance dose is based on TOF / clinical criteria and is 0.03 mg/kg.

Rocuronium 10 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Intubating doses.

  Maintenance is based on TOF / clinical criteria and is 0.1-0.2 mg/kg.

Rocuronium 10 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Normal maintenancedose is 10 – 12 mcg / kg / minute, but can range from 4 – 16 mcg / kg / minute.

Suxametonium 10 mg / ml (Bolus)

• Reference(s): No reference
• Comment:
  NA

Vecuronium 2 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Intubating doses.

  Maintenance is based on TOF / clinical criteria and is 0.01-0.015 mg/kg.

Vecuronium 2 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  NA

Anticholinergic Agent

Anticholinergic Agents.

Atropine 1 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Adults Doses < 0.5 mg have been associated with paradoxical bradycardia. Pediatric doses Doses < 0.1 mg have been associated with paradoxical bradycardia unless below 5 kg.

Glycopyrronium 0.2 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Intraoperative reduction of secretions.

  Full dose to adults. Reference uses 0.1 mg in repeated doses.

Antibiotics

Antibiotics.

Reversal agents

Reversalagents if muscularblockers are used.

Neostigmine 2.5 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Reversal of nondepolarizing neuromuscular blockade.

  Administer anticholinergic agent intravenously minutes prior to Neostigmine.

  Dose depends on TOF / TOF ratio

  Total dose should not exceed 5 mg.

Sugammadex 100 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  NA

Antiemetics

Antiemetics.

Ondansetron 2 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Prevention of PONV.

  Be aware of QT-prolongation.

Antiarrhythmic Agents

Antiarrytmicagents

Adenosine 5 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Initial dose.

  Paroxysmal supraventricular tachycardia.

  Children above 50 Kg refer to adult dosing.

Adenosine Repeatdose 5 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Sequential dose after inital dose.

  Increase initial dose with 0.05 – 0.01 mcg / kg until singledose reaches 0.3 mg / kg or 12 mg.

  Paroxysmal supraventricular tachycardia.

  Children above 50 Kg refer to adult dosing.

Esmolol 10 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Treatment of SVT. According to reference a limited amount of information regarding esmolol use in pediatric patients.

Esmolol 10 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Treatment of SVT. According to reference a limited amount of information regarding esmolol use in pediatric patients.

Alfa+Beta Blockers

Alfabetablockers

Labetalol 5 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Hypertensjon

  Ad adults: Initial dose 25 mg and you may administer 40-80 mg at 10-minute intervals with a cumulative maximum dose of 300 mg.

  Infusion adults : Start with 2 mg/minute and titrate to response up to 300 mg total cumulative dose. That means 2 mg / minute is discontinued after 2.5 hours.

  Ad pediatrics: There is limited documentation of its use in pediatrics patients. Should be initiated cautiously in pediatric patients with careful dosage adjustment and blood pressure monitoring.

Others

Others

Anticoagulantia

NA

Argatroban 1 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Prophylaxis of thrombosis heparininduced thrombocytopenia.

Argatroban 1 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Percutaneous coronary intervention, PCI.

Argatroban 1 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Bolusdoses for adjustment of ACT during infusion of Argatroban.

Platelet aggregation inhibitor

NA

Abciximab 2 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  NA

Abciximab 36 mcg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  NA

Fluids

Fluids. Crystalloids and colloids

Mannitol 150 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  Pediatric

  Reduction of intracranial pressure
  Usual range 0.25g-1g per kilo. Infused over 20 – 30 minutes. See reference

  Reduction intraocular pressure
  1g-2g/kg infused over 30-60 minutes 60-90 minutes prior to surgery. See reference

  Acute renal failure
  0.5g-1g/kg infused over 2-6 hours. See reference

  Adult

  Reduction of intracranial pressure
  Usual range 0.25g-1g per kilo. Infused over 20 – 30 minutes. See reference

  Reduction intraocular pressure
  1g-2g/kg infused over 30-60 minutes 60-90 minutes prior to surgery. See reference

RingerAcetat 1 g / ml (Bolus)

• Reference(s): No reference
• Comment:
  Fluidbolus.

Sodium chloride 9 mg / ml (Infusion)

• Reference(s): No reference
• Comment:
  Fluids. Give mL / Kg / hour and AneIV will calculate mL / h.

Acetylcholinesterase Inhibitor

Acetylcholinesterase Inhibitor

Vasodilators

Drug to induce vasodilation

Nitroglycerin 0.1 mg / ml (Infusion)

• Reference(s): [ 1 ]
• Comment:
  Acute hypertension. Reference is a Swedish site ala rxlist.com. Some modifications. Concentration set to 0.1mg/ml. Shows mcg/kg/min.

Nitroprusside 0.1 mg / ml (Infusion)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Acute hypertension.

  Be aware of toxicity with doses above 2 mcg / kg / minute.

Antidote

Various antidote medications

Flumazenil 0.1 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Pediatrics:
  Infant dosing has minimal data available. Initial dose of 0.01 mg / kg over 15 seconds and same dose 45 seconds later. After that every minute to maximum of 0.05 mg / kg or 1 mg is reached.

  Adults:
  Repeat initial dose every 15 – 30 seconds until four doses has been administered. If target level of consciousness is not obtained, intial dose may be repeated with 1 minute intervals.

  If maximum dose, 1 mg, has been reached, initial dose can be administered with 20 minutes intervals until 1 mg is reached with 3 mg as maximum within an hour.

Analgesics

Analgesics other than opioids

Ketorolac 30 mg / ml (Bolus)

• Reference(s): [ 1 ] [ 2 ]
• Comment:
  Long list of side effetcs See references

  Adults: Dosage adjustment for low body weight < 50 Kg and geriatrics >65 years of age 15 mg.

Paracetamol 10 mg / ml (Bolus)

• Reference(s): [ 1 ]
• Comment:
  These limitations relates to intravenous administration

  Should be used with caution if mild to moderate hepatic impairment or active liver disease is present. See reference.

  Contraindicated if severe hepatic impairment is present.

  See reference if renal impairment is present.

  Pediatrics between 2 and 12 years of age
  15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours. Maximum single dose is 15 mg/kg or 750 mg. Maximum daily dose is 75 mg/kg/day or 3.75g.

  Adults
  If patient weigh less than 50 kilograms, 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours. Maximum single dose is 15 mg/kg or 750 mg, maximum daily dose is 75 mg/kg/day or 3.75g

  If patient weigh more than 50 kilograms, maximum dose is 650 mg every 4 hours or 1000 mg every 6 hours with a maximum daily dose of 4g.